Searchable abstracts of presentations at key conferences in endocrinology

ea0038p367 | Reproduction | SFEBES2015

Characterisation of a GnRH-type signalling system in an echinoderm

Tian Shi , Zandawala Meet , Egertova Michaela , Beets Isabel , Slade Susan E , Scrivens James H , Elphick Maurice R

Gonadotropin-releasing hormone (GnRH) regulates secretion of the reproductive hormones luteinising hormone (LH) and follicle-stimulating hormone (FSH) in mammals. Homologs of GnRH have been identified in protostomian and deuterostomian invertebrates, and functional studies suggest an ancient role in regulation of reproductive physiology. The aim of this study was to characterise for the first time a GnRH-type signalling system in an echinoderm, using the starfish Asterias ...